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Elderly patients warned of Zyprexa risks

-April 12, 2005

The FDA said yesterday that elderly patients with dementia were significantly more likely to die prematurely if taking certain anti-psychotic drugs.

Included in the latest drug warning are schizophrenia and mania drugs Abilify, Zyprexa, Seroquel, Risperdal, Clozaril and Geodon. Symbyax is also included in the advisory, approved for the treatment of depression associated with bipolar disorder.

The FDA asked the drug makers to add a boxed warning to the products, highlighting the risks and noting the drugs are not approved to treat dementia in the elderly. An FDA analysis of 17 studies covering four drugs showed the death rate for the elderly patients taking them was about 1.6 to 1.7 times the death rate for patients taking a placebo.

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