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Pregabalin

Pregabalin, marketed by Pfizer as Lyrica, is a prescription medication used to treat neuropathic pain in people with diabetes (DPN) and shingles (PHN) and as an adjunct therapy for people with partial seizures. After a long battle for FDA approval, the agency finally approved Lyrica in December 2004.

Lyrica was tested on 9,000 patients during pre-marketing clinical trials. The most common risks associated with this medication include: dizziness, blurred vision, sleepiness, weight gain, swelling (edema), muscle problems, and altered perception. Weight gain is of particular concern to those with diabetes, as this can worsen their condition. Lyrica also caused skin sores during animal studies. It is not clear whether this Lyrica side effect applies to humans as well.

Animal studies also showed serious Lyrica side effects in males. Lyrica reduced the fertility of some male animal subjects during testing. Of those males receiving Lyrica that did reproduce, there was a high risk of birth defects in their offspring. It is not clear if these side effects also apply to humans. If you are planning to have a child or get pregnant, it is important to speak with your doctor about the risks of Lyrica.

There are certain medications that can adversely interact with Lyrica. Diabetes drugs, such as Avandia, can cause side effects when used in conjunction with Lyrica. Pain medications (OxyContin) and some anti-anxiety medications can also negatively interact with Lyrica. If you have a history of any medical conditions, or are currently taking other medications or supplements, it is important to discuss these factors with your health care professional before beginning Lyrica.

Please contact us for more information on Pregabalin.

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