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Prilosec (omeprazole, omeprazole magnesium) is a member of the proton pump inhibitor (PPI) family of medications, which help to reduce the production of stomach acid in patients suffering from gastroesophageal reflux disease (GERD), heartburn, and sometimes ulcers. Prilosec was approved by the FDA in 1989 and is sometimes called a precursor to Nexium, another PPI which is also made by AstraZenica.

Recent research out of Stanford University shows that up to 20 million Americans use Prilosec or another PPI to control stomach acid every year. However, our pharmaceutical product liability lawyers have heard from numerous patients who feel that they did not receive adequate warning of potentially serious or even fatal Prilosec side effects.

Prilosec Heart Attack Risk

On June 10, 2015, the journal PLOS One published research from a team of doctors at Stanford University who used data mining to examine the records of 3 million patients to evaluate the potential risk of heart attacks associated with Prilosec and other PPIs. Previous research had suggested that patients taking the blood thinner Plavix in conjunction with Prilosec may be at a higher risk for heart attacks. The Stanford team proved this wrong—Prilosec appears to raise the risk of a heart attack significantly whether a patient takes Plavix or not. In fact, they found that patients taking a PPI like Prilosec are up to 20% more likely to have a heart attack and twice as likely to die from cardiac issues.

When interviewed by Reuters, the lead author of the Stanford study said that this link between Prilosec and heart attacks as "not super surprising", and that this conclusion may have been reached as early as the year 2000 had appropriate data mining technology existed at that time.

Additional Serious Prilosec Side Effects

Along with heart attacks, one of the most alarming Prilosec side effects patients have suffered from is broken bones. A growing body of research shows that Prilosec and other PPIs dramatically increase the likelihood of broken bones, especially hip fractures and especially in older women. The Journal of the American Medical Association noted that patients taking Prilosec may be 2.65 times more likely to suffer a broken hip in 2006. In 2010, the FDA issued a Prilosec bone fracture warning, specifying that broken wrists, hips, and spines were possible and became more likely the longer a patient used a PPI. The British Medical Journal stated in 2012 that post-menopausal women are up to 35% more likely to suffer a broken hip when they use Prilosec or another PPI for an extended period.

In addition to heart attacks, cardiac death, and bone fractures, Prilosec has been associated with the following side effects:

  • Heart arrhythmia
  • Constipation
  • Tremors
  • Muscle spasm
  • Depression
  • Anxiety
  • Itching
  • Nausea
  • Changes in appetite
  • Seizures

Prilosec Side Effects Lawsuits

If you or your loved one has suffered a heart attack, bone fracture, or other serious side effects associated with Prilosec, you may have grounds for a Prilosec lawsuit. We are currently investigating personal injury claims on behalf of plaintiffs who believe that they did not receive sufficient warning of the likelihood or severity of Prilosec side effects. For more information, please contact us today.

Prilosec News

Researcher says Antacid Heart Attack Risk “Not Surprising”

June 24, 2015

Antacids such as Prilosec and Nexium are amongst the most highly used drugs in the United States, with up to 20 million Americans using these medications every year. Thus, it likely shocked many patients when earlier this month researchers from Stanford University published a study … Full Story

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